Regulatory
Part:BBa_K105028:Design
Designed by: Michael Wild Group: iGEM08_ESBS-Strasbourg (2008-10-26)
cyc70 minimal promoter
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
This BioBrick contains the TATA-box with one point mutation and most of the 5'UTR (-139 to -36, relative to the translational start) of the natural CYC1 promoter. A Kozak sequence is not included and has thus to be added!
Even if there isn't any need for this BioBrick to be fusible to other protein domains, we stayed with our design.
Source
Amplification and Mutation from the plasmid pAH3
References
Gudrun Bjornsdottir & Lawrence C. Myers (2008) Nucleic Acids Research 9 2906-2916.